Returns every mob in the world matching the given vnum. If you just want to know how many of something there are (a common use) you can say
if(npc_in_world(1000),length(npc_in_world(1000)),0)
This function returns null if there aren't any. Therefore, if you just want to test for the presence of one or more in an if, you can say
if(npc_in_world(1000), ...